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Correlation between neuropsychologic...

Nova Southeastern University., Psychology.

Correlation between neuropsychological tests and MRI findings in mild cognitive impairment.

紀錄類型:	書目-電子資源 : 單行本
正題名/作者:	Correlation between neuropsychological tests and MRI findings in mild cognitive impairment./
作者:	Roberts, Darci M.
面頁冊數:	134 p.
附註:	Source: Dissertation Abstracts International, Volume: 69-11, Section: B, page: 7148.
Contained By:	Dissertation Abstracts International69-11B.
標題:	Biology, Neuroscience. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoeng/servlet/advanced?query=3331343
ISBN:	9780549893103

Correlation between neuropsychological tests and MRI findings in mild cognitive impairment.
Roberts, Darci M.

Correlation between neuropsychological tests and MRI findings in mild cognitive impairment. - 134 p.

Source: Dissertation Abstracts International, Volume: 69-11, Section: B, page: 7148.

Thesis (Ph.D.)--Nova Southeastern University, 2007.

Geriatric populations are exceeding previously established life expectancies, and with these changes, diseases such as mild cognitive impairment (MCI) and Alzheimer's dementia (AD) are becoming more prevalent. Increased efforts must be made by healthcare professionals to better understand age-related cognitive disorders. This study examined the relationship between cognitive impairment and magnetic resonance imaging (MRI) results in a group of patients with MCI and normal age-matched controls. Twenty-five patients with MCI and twenty-three normal geriatric adults received a comprehensive interview, neuropsychological assessment, and MRI imaging. Neuropsychological measures included a verbal memory measure (the Logical Memory subtest of the Wechsler Memory Scale-III) and a visual memory measure (the Visual Reproduction subtest of the Wechsler Memory Scale-Revised), along with other commonly administered neuropsychological assessments (Block Design from the Wechsler Adult Intelligence Scale-III, Category Fluency, FAS Controlled Oral Word Association test, and the Trail Making Test). Neuroimaging included MRI ratings of the left and right temporal lobe, frontal lobe, and hippocampus. Neuropsychological test scores and MRI atrophy ratings of the two groups were compared. In addition, correlations between neuropsychological tests and MRI findings were assessed. Mean scores obtained by the MCI group for each of the neuropsychological tests were significantly lower than the normal control group, as were the MRI atrophy ratings for both temporal lobes and the right frontal lobe. Significant correlations were found between visual memory and atrophy ratings of the right temporal lobes, verbal memory and atrophy ratings of the left frontal lobe, and Block Design performance and the frontal lobes. In addition, significant correlations were found between verbal memory and hippocampal atrophy, visual memory and hippocampal atrophy, and Category Fluency and hippocampal atrophy. Based on this research, it is evident that both neuropsychological tests and neuroimaging may be useful in identifying and characterizing MCI. Although most literature focuses on one method of assessment or the other, utilization of these techniques in conjunction with one another may be helpful. In order to appropriately diagnose, treat, and identify prognosis of this disorder, research should focus on these methods together rather than separately.

ISBN: 9780549893103Subjects--Topical Terms:

1000005467
Biology, Neuroscience.

Correlation between neuropsychological tests and MRI findings in mild cognitive impairment.
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