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The effect of early life events on t...

Brenes, Gilbert.

The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections.

レコード種別:	コンピュータ・メディア : 単行資料
タイトル / 著者:	The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections./
著者:	Brenes, Gilbert.
記述:	208 p.
注記:	Source: Dissertation Abstracts International, Volume: 69-05, Section: A, page: 1997.
含まれています:	Dissertation Abstracts International69-05A.
主題:	Gerontology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3314166
国際標準図書番号 (ISBN):	9780549636816

The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections.
Brenes, Gilbert.

The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections. - 208 p.

Source: Dissertation Abstracts International, Volume: 69-05, Section: A, page: 1997.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2008.

During their childhood years, current cohorts of Latin American elderly experienced an environment characterized by economic deprivation, malnutrition, and high prevalence of infectious diseases, but survived to old age due to the introduction of medical technology and public health measures (Palloni, 1981). In light of the thrifty phenotype hypothesis (Hales and Barker, 1992; 2001), people that were undernourished during gestation and early childhood are more likely to develop Type II Diabetes Mellitus (DM). Given the high prevalence of these conditions among current Latin American elderly cohorts, Palloni et al. (2006) and Prentice and Moore (2005) have hypothesized that there might be an epidemic of DM.

ISBN: 9780549636816Subjects--Topical Terms:

168436
Gerontology.

The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections.
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245 1 4 $a The effect of early life events on the burden of diabetes mellitus among Costa Rican elderly: Estimates and projections.
300 $a 208 p.
500 $a Source: Dissertation Abstracts International, Volume: 69-05, Section: A, page: 1997.
500 $a Adviser: Alberto Palloni.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2008.
520 $a During their childhood years, current cohorts of Latin American elderly experienced an environment characterized by economic deprivation, malnutrition, and high prevalence of infectious diseases, but survived to old age due to the introduction of medical technology and public health measures (Palloni, 1981). In light of the thrifty phenotype hypothesis (Hales and Barker, 1992; 2001), people that were undernourished during gestation and early childhood are more likely to develop Type II Diabetes Mellitus (DM). Given the high prevalence of these conditions among current Latin American elderly cohorts, Palloni et al. (2006) and Prentice and Moore (2005) have hypothesized that there might be an epidemic of DM.
520 $a The goal of this dissertation is to estimate the effect of early childhood conditions on DM burden among the population 60 years old and older in Costa Rica, and to project the prevalence of DM among this population for the period 2005--2030. I use short knee height (KH) and the level of childhood mortality (CMI) in the respondents' place of birth as surrogate markers of malnutrition during gestation and infancy.
520 $a I find that there is weak but significant effect of KH on DM incidence, but only when having short KH interacts with obesity. Being born in high CMI counties is positively associated with having high levels of glucose or glycosylated hemoglobin. The projected DM burden among Costa Rican elderly shows that the population age 60 years old and older with DM in Costa Rica is going to quadruple in the next 25 years, but this increase is basically due to the growth in the total elderly population.
520 $a I conclude that Costa Rica is going to have a sharp increase in the burden of DM among its senior population, but that this increase is related to population increase rather than to adverse health conditions during childhood. I argue that for other Latin American countries this increase in DM might happen if the same cohorts in those countries experienced adverse early childhood conditions and malnutrition, as well as obesity.
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