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Face processing in persons with and ...

Florida Atlantic University.

Face processing in persons with and without Alzheimer's disease.

レコード種別:	コンピュータ・メディア : 単行資料
タイトル / 著者:	Face processing in persons with and without Alzheimer's disease./
著者:	Winchester, Jeanna.
記述:	89 p.
注記:	Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2219.
含まれています:	Dissertation Abstracts International71-04B.
主題:	Biology, Neuroscience. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3401883
国際標準図書番号 (ISBN):	9781109695083

Face processing in persons with and without Alzheimer's disease.
Winchester, Jeanna.

Face processing in persons with and without Alzheimer's disease. - 89 p.

Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2219.

Thesis (Ph.D.)--Florida Atlantic University, 2009.

This study aimed to understand the differences in strength or coordination of brain regions involved in processing faces in the presence of aging and/or progressing neuropathology (Alzheimer's disease). To this end, Experiment 1 evaluated age-related differences in basic face processing and the effects of familiarity in face processing. Overall, face processing in younger (22--35yrs) and older participants (63--83yrs) recruited a broadly distributed network of brain activity, but the distribution of activity varied depending on the age of the individual. The younger population utilized regions of the occipitotemporal, medial frontal and posterior parietal cortices while the older population recruited a concentrated occipitotemporal network. The younger participants were also sensitive to the type of face presented, as Novel faces were associated with greater mean BOLD activity than either the Famous or Relatives faces. Interestingly, Relatives faces were associated with greater mean BOLD activity in more regions of the brain than found in any other analysis in Exp. 1, spanning the inferior frontal, medial temporal and inferior parietal cortices. In contrast, the older adults were not sensitive to the type of face presented, which could reflect a difference in cognitive strategies used by the older population when presented with this type of face stimuli. Experiment 2 evaluated face processing, familiarity in face processing and also emphasized the interactive roles autobiographical processing and memory recency play in processing familiar faces in mature adults (MA; 45--55yrs), older adults (OA; 70--92yrs) and patients suffering from Alzheimer's disease (AD; 70--92yrs). MA participants had greater mean BOLD activity values in more regions of the brain than observed in either of the older adult populations, spanning regions of the medial frontal, medial temporal, inferior parietal and occipital cortices. OA, in contrast, utilized a concentrated frontal and medial temporal network and AD participants had the greatest deficit in BOLD activity overall. Age-related differences in processing faces, in processing the type of face presented, in autobiographical information processing and in processing the recency of a memory were noted, as well as differences due to the deleterious effects of AD.

ISBN: 9781109695083Subjects--Topical Terms:

1000005467
Biology, Neuroscience.

Face processing in persons with and without Alzheimer's disease.
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245 1 0 $a Face processing in persons with and without Alzheimer's disease.
300 $a 89 p.
500 $a Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2219.
500 $a Adviser: Betty Tuller.
502 $a Thesis (Ph.D.)--Florida Atlantic University, 2009.
520 $a This study aimed to understand the differences in strength or coordination of brain regions involved in processing faces in the presence of aging and/or progressing neuropathology (Alzheimer's disease). To this end, Experiment 1 evaluated age-related differences in basic face processing and the effects of familiarity in face processing. Overall, face processing in younger (22--35yrs) and older participants (63--83yrs) recruited a broadly distributed network of brain activity, but the distribution of activity varied depending on the age of the individual. The younger population utilized regions of the occipitotemporal, medial frontal and posterior parietal cortices while the older population recruited a concentrated occipitotemporal network. The younger participants were also sensitive to the type of face presented, as Novel faces were associated with greater mean BOLD activity than either the Famous or Relatives faces. Interestingly, Relatives faces were associated with greater mean BOLD activity in more regions of the brain than found in any other analysis in Exp. 1, spanning the inferior frontal, medial temporal and inferior parietal cortices. In contrast, the older adults were not sensitive to the type of face presented, which could reflect a difference in cognitive strategies used by the older population when presented with this type of face stimuli. Experiment 2 evaluated face processing, familiarity in face processing and also emphasized the interactive roles autobiographical processing and memory recency play in processing familiar faces in mature adults (MA; 45--55yrs), older adults (OA; 70--92yrs) and patients suffering from Alzheimer's disease (AD; 70--92yrs). MA participants had greater mean BOLD activity values in more regions of the brain than observed in either of the older adult populations, spanning regions of the medial frontal, medial temporal, inferior parietal and occipital cortices. OA, in contrast, utilized a concentrated frontal and medial temporal network and AD participants had the greatest deficit in BOLD activity overall. Age-related differences in processing faces, in processing the type of face presented, in autobiographical information processing and in processing the recency of a memory were noted, as well as differences due to the deleterious effects of AD.
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856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3401883

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